A55004

4-(2-Aminoethyl)morpholine

99%

• Synonym(s): 2-Morpholinoethylamine
• Empirical Formula (Hill Notation): C₆H₁₄N₂O
• CAS Number: 2038-03-1
• Molecular Weight: 130.19
• Beilstein/REAXYS Number: 104378
• EC Number: 218-011-6
• MDL number: MFCD00006182
• UNSPSC Code: 12352100
• PubChem Substance ID: 24890978
• NACRES: NA.22

Properties

• assay: 99%
• form: solid
• refractive index: n20/D 1.476 (lit.)
• bp: 205 °C (lit.)
• density: 0.992 g/mL at 25 °C (lit.)
• SMILES string: NCCN1CCOCC1
• InChI: 1S/C6H14N2O/c7-1-2-8-3-5-9-6-4-8/h1-7H2
• InChI key: RWIVICVCHVMHMU-UHFFFAOYSA-N

Description

Application

4-(2-Aminoethyl)morpholine is widely used in biomedical applications as this moiety serves as an important lysosome-targeting group. Some of its applications include:

• Synthesis of the lysosome-targetable fluorescent probe for hydrogen sulfide imaging in living cells.
• Synthesis of 1,8-naphthalimide conjugated Troger′s bases as deoxyribonucleic acid (DNA) targeting fluorescent probe.
• Synthesis of intramolecular charge transfer-photoinduced electron transfer-fluorescence resonance energy transfer (ICT-PET-FRET) fluorescent probe for monitoring pH changes in living cells.
• It is also used as a precursor to synthesize a variety of antimicrobial agents.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H314,H317
• pcodes: P260 - P272 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Skin Corr. 1B - Skin Sens. 1
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 2
• flash_point_f: 186.8 °F - closed cup
• flash_point_c: 86 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges