936405

Fmoc-Val-Cit-PAB-OH

≥95%

• Synonym(s): N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N⁵-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide, L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N⁵-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]
• Empirical Formula (Hill Notation): C₃₃H₃₉N₅O₆
• CAS Number: 159858-22-7
• Molecular Weight: 601.69
• MDL number: MFCD22417106
• UNSPSC Code: 12352116
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥95%
• form: solid
• color: white to off-white
• storage temp.: 2-8°C
• SMILES string: OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O
• InChI: InChI= 1S/C33H39N5O6/c1-20(2)29(38-33(43)44-19-27-25-10-5-3-8-23(25)24-9-4-6-11-26(24)27)31(41)37-28(12-7-17-35-32(34)42)30(40)36-22-15-13-21(18-39)14-16-22/h3-6,8-11,13-16,20,27-29,39H,7,12,17-19H2,1-2H3,(H,36,40)(H,37,41)(H,38,43)(H3,34,35,42)/t28-,29-/m0/s1

Description

Application

This is a cathepsin cleavable linker used in the construction of antibody drug conjugates (ADC & Bioconjugation).

Other Notes

Bifunctional Cathepsin cleaveable linkers

ADC & Bioconjugation

Chemical Biology Tools

Impact of linker length on the activity of PROTACs

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable