930741

Poly(oligoethylene glycol methacrylate)

• Synonym(s): POEGMA, Poly(oligo(ethylene glycol)methacrylate)
• Linear Formula: C₆H₈NO₂[C₄H₅O₂(C₂H₄O)_x]_nOH
• UNSPSC Code: 12352104
• NACRES: NA.21

Properties

• form: liquid
• Quality Level: 100
• mol wt: 80,000-130,000
• color: colorless
• storage temp.: −20°C

Description

General description

Poly(oligo(ethylene glycol) methacrylate) (POEGMA) is a family of polymers consisting of a hydrophobic methacrylate backbone and hydrophilic ethylene oxide (EO) side groups with highly branched architecture. The highly branched architecture with a high density of oligo EO moities enhances the solubility of the polymer in water.

Application

• Drug delivery- enhances the stability and delivery of siRNA and eliminates PEG antigenicity
• Biosensor coatings- provides an anti-fouling surface
• Stimuli-responsive hydrogels for tissue engineering, drug delivery, and other biomedical applications

Poly(oligo(ethylene glycol) methyl ether methacrylate) (POEGMA) is a family of polymers consisting of a hydrophobic methacrylate backbone and hydrophilic ethylene oxide (EO) side groups with highly branched architecture . The side chain EO segments enhance the solubility of the polymer in water , exhibiting many interesting properties such as non-fouling , stealth, anti-PEG antibodies & thermo-responsive behaviors.

Features and Benefits

• Highly branched architecture and high density of oligo ethylene oxide moieties
• Water soluble
• Nonfouling and thermo-responsive behaviors
• Viable alternative to PEG in biological and biomaterial applications

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable