902128

(Z)-N′-Cyanopicolinimidamide

• Synonym(s): Weix 2-pyridyl-N-cyanocarboxamidine ligand for nickel catalysis
• Empirical Formula (Hill Notation): C₇H₆N₄
• CAS Number: 89795-81-3
• Molecular Weight: 146.15
• MDL number: MFCD11227164
• UNSPSC Code: 12352111

Properties

• form: powder or crystals
• reaction suitability: reagent type: catalyst; reaction type: Cross Couplings; reagent type: ligand
• mp: 201-205 °C
• SMILES string: N\C(=N\C#N)\c1ncccc1
• InChI: 1S/C7H6N4/c8-5-11-7(9)6-3-1-2-4-10-6/h1-4H,(H2,9,11)
• InChI key: HMQYOLLIJRIQNB-UHFFFAOYSA-N

Description

Application

This pyridyl carboxamidine ligand has been demonstrated by Daniel Weix′s lab to enable nickel-catalyzed cross-coupling of diverse basic nitrogen heterocycles with primary and secondary alkyl halides.

Other Notes

Coupling of Challenging Heteroaryl Halides with Alkyl Halides via Nickel-Catalyzed Cross-Electrophile Coupling

New ligands for nickel catalysis from diverse pharmaceutical heterocycle libraries

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable