900662
Poly(D,L-lactide-co-glycolide)(85/15)-b-poly(ethylene glycol)-carboxylic acid
5k-13k
Synonym(s):
PLGA-PEG, PLGA-PEG Carboxylic acid diblock copolymer, PLGA-PEG-COOH, PLGA-b-PEG
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Application
Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic Poly(lactide-co-glycolide) (PLGA) block, functionalized with a terminal carboxylic acid. These materials have been used in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Additionally, the ratio of lactide to glycolide can be tuned to control rate of degradation. Carboxylic acid termination allows for facile further chemical modification of these materials.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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