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Key Documents

77787

Sigma-Aldrich

O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol

≥90% (oligomer purity)

Synonym(s):

Azido-PEG-amine (n=10)

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About This Item

Empirical Formula (Hill Notation):
C22H46N4O10
CAS Number:
Molecular Weight:
526.62
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥90% (oligomer purity)

form

liquid

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

functional group

amine
azide

storage temp.

2-8°C

SMILES string

NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

InChI

1S/C22H46N4O10/c23-1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-21-22-36-20-18-34-16-14-32-12-10-30-8-6-28-4-2-25-26-24/h1-23H2

InChI key

RMNAJNJBCBFOKX-UHFFFAOYSA-N

Application

O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol may be used in the synthesis of potent PEGylated toll like receptor 7 (TLR7) ligand with improved solubility and modulated protein binding.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Synthesis and characterization of PEGylated toll like receptor 7 ligands.
Chan M, et al.
Bioconjugate Chemistry, 22(3), 445-454 (2011)

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