759171

CPhos

98%

• Synonym(s): 2-Dicyclohexylphosphino-2′,6′-bis(N,N-dimethylamino)biphenyl
• Empirical Formula (Hill Notation): C₂₈H₄₁N₂P
• CAS Number: 1160556-64-8
• Molecular Weight: 436.61
• MDL number: MFCD27978504
• UNSPSC Code: 12352116
• PubChem Substance ID: 329766759
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• form: solid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand; reaction type: Cross Couplings
• mp: 108-113 °C
• functional group: phosphine
• SMILES string: CN(C)C(C=CC=C1N(C)C)=C1C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4
• InChI: 1S/C28H41N2P/c1-29(2)25-19-13-20-26(30(3)4)28(25)24-18-11-12-21-27(24)31(22-14-7-5-8-15-22)23-16-9-6-10-17-23/h11-13,18-23H,5-10,14-17H2,1-4H3
• InChI key: DRNAQRXLOSUHBQ-UHFFFAOYSA-N

Description

Application

CPhos can be used:

• As a ligand in the Pd-catalyzed synthesis of 3-cyclopentylindole derivatives, dihydrobenzofurans and trans-bicyclic sulfamides.
• To synthesize palladacycle precatalysts for Negishi coupling of secondary alkylzinc.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315 - H319 - H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable