673013

2-Benzyloxyphenylmagnesium bromide solution

1.0 M in THF

• Empirical Formula (Hill Notation): C₁₃H₁₁BrMgO
• CAS Number: 328000-16-4
• Molecular Weight: 287.43
• MDL number: MFCD08705262
• UNSPSC Code: 12352103
• PubChem Substance ID: 24885138
• NACRES: NA.22

Properties

• reaction suitability: reaction type: Grignard Reaction
• Quality Level: 100
• concentration: 1.0 M in THF
• density: 1.047 g/mL at 25 °C
• functional group: phenyl
• SMILES string: Br[Mg]c1ccccc1OCc2ccccc2
• InChI: 1S/C13H11O.BrH.Mg/c1-3-7-12(8-4-1)11-14-13-9-5-2-6-10-13;;/h1-9H,11H2;1H;/q;;+1/p-1
• InChI key: VELKJPFZDYXBDE-UHFFFAOYSA-M

Description

Application

2-Benzyloxyphenylmagnesium bromide can be used:

• As a substrate in the iron-catalyzed coupling reaction of aryl Grignard reagents with unprotected bromophenols.
• As a substrate in the cross-coupling of Grignard reagents using diaryl titanates and ferric chloride.
• In one of the key synthetic steps for the total synthesis of an antibiotic caboxamycin.

Safety Information

• pictograms: GHS02,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H302,H314,H335,H351
• pcodes: P210 - P260 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH014,EUH019
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: -4.0 - 5.0 °F - closed cup
• flash_point_c: -20 - -15 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter