665150

Ethyl N-Boc-piperidine-4-carboxylate

97%

• Synonym(s): Ethyl 1-(tert-Butyloxycarbonyl)isonipecotate, Ethyl 1-(tert-butoxycarbonyl)-4-piperidinecarboxylate, Piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester
• Empirical Formula (Hill Notation): C₁₃H₂₃NO₄
• CAS Number: 142851-03-4
• Molecular Weight: 257.33
• MDL number: MFCD01763998
• UNSPSC Code: 12352100
• PubChem Substance ID: 24884718
• NACRES: NA.22

Properties

• assay: 97%
• refractive index: n20/D 1.458
• bp: 120-135 °C/0.5 mmHg
• density: 1.046 g/mL at 25 °C
• SMILES string: CCOC(=O)C1CCN(CC1)C(=O)OC(C)(C)C
• InChI: 1S/C13H23NO4/c1-5-17-11(15)10-6-8-14(9-7-10)12(16)18-13(2,3)4/h10H,5-9H2,1-4H3
• InChI key: MYHJCTUTPIKNAT-UHFFFAOYSA-N

Description

Application

Substrate used in a palladium-catalyzed α-arylation of esters with heterocyclic bromides and chlorides leading to, for example, 4-pyridylpiperidinyl esters.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H315,H318,H335
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: >230.0 °F - closed cup
• flash_point_c: > 110 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter