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635936

Sigma-Aldrich

N-Cyclohexylhydroxylamine

Synonym(s):

N-Hydroxycyclohexanamine, N-Hydroxycyclohexylamine

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About This Item

Linear Formula:
C6H11NHOH
CAS Number:
Molecular Weight:
115.17
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

form

solid

mp

139-140 °C (lit.)

storage temp.

−20°C

SMILES string

ONC1CCCCC1

InChI

1S/C6H13NO/c8-7-6-4-2-1-3-5-6/h6-8H,1-5H2

InChI key

GUQRKZPMVLRXLT-UHFFFAOYSA-N

General description

N-Cyclohexylhydroxylamine is formed as one of the by-products during the hydrogenation of nitrocyclohexane to the corresponding cyclohexanone oxime catalyzed by palladium/carbon nanotubes.

Application

Reactant for:
  • Aldehyde-catalyzed intermolecular hydroamination
  • Condensation reactions
  • Preparation of cyclin-dependent kinase inhibitors selective for multiple cyclin-dependent kinases for potential use as antitumor agents
  • Preparation of hydroxyurea derivatives as small molecule bradykinin B1 receptor antagonists

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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"Hydrogenation of nitrocyclohexane to cyclohexanone oxime over Pd/CNT catalyst under mild conditions"
Liao G-H, et al.
Catalysis Communications, 19, 80-84 (2012)

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