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Key Documents

53695

Sigma-Aldrich

3-(Tritylthio)propionic acid

≥97.0% (T)

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About This Item

Linear Formula:
(C6H5)3CSCH2CH2COOH
CAS Number:
Molecular Weight:
348.46
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥97.0% (T)

SMILES string

OC(=O)CCSC(c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C22H20O2S/c23-21(24)16-17-25-22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15H,16-17H2,(H,23,24)

InChI key

AECGEIVNZGQBJT-UHFFFAOYSA-N

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

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Mathew R Schnorenberg et al.
ACS omega, 3(10), 14144-14150 (2018-11-10)
Despite the therapeutic promise of phospholipid-based nanocarriers, a major obstacle to their widespread clinical translation is a susceptibility to fatty acid ester hydrolysis, leading to lack of quality control and inconsistencies in self-assembly formulations. Using electrospray ionization mass spectrometry fragmentation
Naglaa Salem El-Sayed et al.
Molecules (Basel, Switzerland), 24(7) (2019-04-14)
Cell-penetrating peptide [WR]₅ has been previously shown to be an efficient molecular transporter for various hydrophilic and hydrophobic molecules. The peptide was synthesized using Fmoc/tBu solid-phase chemistry, and one arginine was replaced with one lysine to enable the conjugation with
Partha Laskar et al.
Nanoscale, 11(42), 20058-20071 (2019-10-16)
Combination therapy involving chemotherapeutic drugs and genes is emerging as a promising strategy to provide a synergistic therapeutic effect, to overcome drug resistance while reducing the severe side effects associated with conventional chemotherapeutic drugs. However, the lack of nanomedicines able
Scott H Medina et al.
Journal of controlled release : official journal of the Controlled Release Society, 209, 317-326 (2015-05-17)
Many lead molecules identified in drug discovery campaigns are eliminated from consideration due to poor solubility and low cell permeability. These orphaned molecules could have clinical value if solubilized and delivered properly. SVS-1 is a de novo designed peptide that

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