464821

(R)-(+)-3-Butyn-2-ol

98%

• Linear Formula: HC≡CCH(OH)CH₃
• CAS Number: 42969-65-3
• Molecular Weight: 70.09
• MDL number: MFCD00211237
• UNSPSC Code: 12352003
• PubChem Substance ID: 24870225
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• optical activity: [α]22/D +45°, neat
• refractive index: n20/D 1.426 (lit.)
• bp: 108-111 °C (lit.)
• density: 0.89 g/mL at 25 °C (lit.)
• functional group: hydroxyl
• SMILES string: C[C@@H](O)C#C
• InChI: 1S/C4H6O/c1-3-4(2)5/h1,4-5H,2H3/t4-/m1/s1
• InChI key: GKPOMITUDGXOSB-SCSAIBSYSA-N

Description

Application

(R)-(+)-3-Butyn-2-ol may be used as a starting material in the multi-step synthesis of (R)-benzyl 4-hydroxyl-2-pentynoate.

Propargylic alcohols are important starting materials for new classes of second generation 5-lipoxygenase inhibitors.

Used in a ruthenium-catalyzed polymerization providing helical polyacetylenes.

Safety Information

• pictograms: GHS02,GHS06,GHS08,GHS05
• signalword: Danger
• hcodes: H226,H300 + H330,H315,H317,H318,H335,H351
• pcodes: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 78.8 °F - closed cup
• flash_point_c: 26 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter