441058

(1R)-(−)-Menthyl acetate

98%

• Synonym(s): (-)-Menthol acetate, (-)-Menthyl acetate, (-)-p-Menthyl acetate, (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexanol acetate, Acetic acid (R)-menthyl ester, L-Menthyl acetate, l-(-)-Menthyl acetate, l-Menthol acetate
• Empirical Formula (Hill Notation): C₁₂H₂₂O₂
• CAS Number: 2623-23-6
• Molecular Weight: 198.30
• Beilstein/REAXYS Number: 2208505
• EC Number: 220-076-0
• MDL number: MFCD00001482
• UNSPSC Code: 12352108
• PubChem Substance ID: 24867639
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• form: liquid
• optical activity: [α]20/D −81°, c = 8 in benzene
• optical purity: ee: 98% (GLC)
• refractive index: n20/D 1.447 (lit.)
• bp: 229-230 °C (lit.)
• density: 0.92 g/mL at 25 °C (lit.)
• functional group: ester
• SMILES string: CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(C)=O
• InChI: 1S/C12H22O2/c1-8(2)11-6-5-9(3)7-12(11)14-10(4)13/h8-9,11-12H,5-7H2,1-4H3/t9-,11+,12-/m1/s1
• InChI key: XHXUANMFYXWVNG-ADEWGFFLSA-N

Description

Application

• RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified): This safety assessment covers the toxicity data on menthyl acetate, indicating low toxicity and providing a foundation for safe usage in fragrances and related products (AM Api et al., 2017).


• The crystalline sponge method: MOF terminal ligand effects: This article discusses the inclusion of (1R)-(−)-menthyl acetate into Metal-Organic Frameworks (MOFs) and analyzes its interactions and structural integration (TR Ramadhar et al., 2015).


• Engineering a Bacillus subtilis esterase for selective hydrolysis of d, l-menthyl acetate in an organic solvent-free system: This research engineered a variant of Bacillus subtilis esterase that shows enhanced selectivity and efficiency in the hydrolysis of d, l-menthyl acetate, suitable for industrial applications (J Qiao et al., 2023).

Safety Information

• pictograms: GHS09
• hcodes: H411
• pcodes: P273 - P391 - P501
• Hazard Classifications: Aquatic Chronic 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: 170.6 °F - closed cup
• flash_point_c: 77 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter