440841

(1R,2S)-(+)-cis-1-Amino-2-indanol

99%

• Synonym(s): (1R,2S)-(+)-cis-1-Amino-2-hydroxyindane
• Empirical Formula (Hill Notation): C₉H₁₁NO
• CAS Number: 136030-00-7
• Molecular Weight: 149.19
• Beilstein/REAXYS Number: 2803743
• MDL number: MFCD00216656
• UNSPSC Code: 12352116
• PubChem Substance ID: 24867628
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 99%
• form: solid
• optical activity: [α]22/D +63°, c = 0.2 in chloroform
• optical purity: ee: 99% (GLC)
• mp: 118-121 °C (lit.)
• functional group: hydroxyl
• SMILES string: N[C@H]1[C@@H](O)Cc2ccccc12
• InChI: 1S/C9H11NO/c10-9-7-4-2-1-3-6(7)5-8(9)11/h1-4,8-9,11H,5,10H2/t8-,9+/m0/s1
• InChI key: LOPKSXMQWBYUOI-DTWKUNHWSA-N

Description

Application

This cis-aminoindanol and its antipode have been used in the preparation of a series of potent HIV-1 protease inhibitory peptides. Also, they have served as chiral ligands in the catalytic asymmetric reduction of prochiral ketones with boranes.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves