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434248

Sigma-Aldrich

L-Abrine

99%

Synonym(s):

Nα-Methyl-L-tryptophan

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About This Item

Empirical Formula (Hill Notation):
C12H14N2O2
CAS Number:
526-31-8
Molecular Weight:
218.25
Beilstein/REAXYS Number:
86638
EC Number:
208-388-5
MDL number:
MFCD00005645
UNSPSC Code:
41116107
PubChem Substance ID:
24867181
NACRES:
NA.22

assay

99%

optical activity

[α]20/D +65°, c = 1 in 0.5 M NaOH

reaction suitability

reaction type: solution phase peptide synthesis

mp

>300 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

CN[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI

1S/C12H14N2O2/c1-13-11(12(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,13-14H,6H2,1H3,(H,15,16)/t11-/m0/s1

InChI key

CZCIKBSVHDNIDH-NSHDSACASA-N

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Biochem/physiol Actions

An indoleamino acid that shows radical scavenging and antioxidant properties in vitro.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCP6577
MKCM1504
MKCL9554
MKCG7460
MKCB0357V

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Maximilian Huber et al.
The Science of the total environment, 541, 895-919 (2015-10-09)
A dataset of 294 monitored sites from six continents (Africa, Asia, Australia, Europe, North and South America) was compiled and evaluated to characterize the occurrence and fate of heavy metals in eight traffic area categories (parking lots, bridges, and three
Emilie Gauthy et al.
PloS one, 8(9), e76186-e76186 (2013-10-08)
GARP is a transmembrane protein present on stimulated human regulatory T lymphocytes (Tregs), but not on other T lymphocytes (Th cells). It presents the latent form of TGF-β1 on the Treg surface. We report here that GARP favors the cleavage
Huixi Zou et al.
Journal of natural products, 72(1), 44-52 (2008-12-31)
This study reports that a series of tryptophan derivatives with modifications on the side chain or at the indole ring were accepted by two cyclic dipeptide prenyltransferases, CdpNPT and FtmPT1, and converted to prenylated derivatives. The structures of the enzymatic

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