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Sigma-Aldrich

PAMAM dendrimer, ethylenediamine core, generation 1.0 solution

20 wt. % in methanol

Synonym(s):

PAMAM dendrimer (G-1)

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About This Item

Linear Formula:
[NH2(CH2)2NH2]:(G=1);dendri PAMAM(NH2)8
CAS Number:
142986-44-5
Molecular Weight:
1429.85
MDL number:
MFCD00192448
UNSPSC Code:
12162002
PubChem Substance ID:
329756075
NACRES:
NA.23

description

amino surface groups

form

liquid

mol wt

generation 1.0

feature

core type ethylenediamine core (2-carbon core)

concentration

20 wt. % in methanol

no. Surface Groups

8

refractive index

n20/D 1.362

bp

64.7 °C

density

0.82 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

NCCNC(=O)CCN(CCNC(=O)CCN(CCN(CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN

InChI

1S/C62H128N26O12/c63-13-21-71-51(89)1-33-83(34-2-52(90)72-22-14-64)45-29-79-59(97)9-41-87(42-10-60(98)80-30-46-84(35-3-53(91)73-23-15-65)36-4-54(92)74-24-16-66)49-50-88(43-11-61(99)81-31-47-85(37-5-55(93)75-25-17-67)38-6-56(94)76-26-18-68)44-12-62(100)82-32-48-86(39-7-57(95)77-27-19-69)40-8-58(96)78-28-20-70/h1-50,63-70H2,(H,71,89)(H,72,90)(H,73,91)(H,74,92)(H,75,93)(H,76,94)(H,77,95)(H,78,96)(H,79,97)(H,80,98)(H,81,99)(H,82,100)

InChI key

QVWIZHOFYGKROL-UHFFFAOYSA-N

Application

  • Gold-Dendrimer Nanocomposites: Study on the synthesis and morphological characterization of gold-dendrimer nanocomposites using PAMAM dendrimers with ethylenediamine cores, evaluating their potential biomedical applications (Vasile, Serafim, Petre, Giol, 2014).
  • DNA Interaction Modeling: Analysis of complexes formed between DNA and poly(amido amine) dendrimers of different generations, focusing on modeling DNA wrapping and penetration which includes Generation 1.0 dendrimers (Qamhieh, Nylander, Black, Attard, 2014).

Physical form

Contains 8 surface primary amino groups

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 1 - STOT SE 3

target_organs

Eyes,Central nervous system, Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

51.8 °F

flash_point_c

11 °C

Certificates of Analysis (COA)

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Solubility Enhancement of Poorly Water Soluble Molecules Using Dendrimers

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