384305

6-Hydroxypyridine-2-carboxylic acid

95%

• Synonym(s): 6-Hydroxypicolinic acid, 6-Hydroxypyridine-2-carboxylic acid
• Empirical Formula (Hill Notation): C₆H₅NO₃
• CAS Number: 19621-92-2
• Molecular Weight: 139.11
• Beilstein/REAXYS Number: 115842
• MDL number: MFCD00192220
• UNSPSC Code: 12352100
• PubChem Substance ID: 24863659
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 95%
• form: solid
• mp: 270 °C (dec.) (lit.)
• functional group: carboxylic acid
• SMILES string: OC(=O)c1cccc(O)n1
• InChI: 1S/C6H5NO3/c8-5-3-1-2-4(7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)
• InChI key: VRCWSYYXUCKEED-UHFFFAOYSA-N

Description

General description

6-Hydroxypyridine-2-carboxylic acid (6HPA, 6-Hydroxypicolinic acid) is a picolinic acid derivative. It has been reported to exhibit enol-keto tautomerism. It is a chelating ligand exhibiting potential complexing ability (via N,O-chelation or N,O,O-chelation). Intramolecular proton transfer (IPT) in tautomeric forms of 6HPA has been investigated by density functional theory (DFT) calculations.

Application

6-Hydroxypyridine-2-carboxylic acid may be used in the preparation of ruthenium(II) complex, [RuH(CO)(6-OH-py-2-COO)(PPh₃)₂].

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves