381985

Nysted Reagent

20 wt. % suspension in THF

• Synonym(s): cyclo-Dibromodi-μ-methylene[μ-(tetrahydrofuran)]trizinc
• Empirical Formula (Hill Notation): C₆H₁₂Br₂OZn₃
• CAS Number: 41114-59-4
• Molecular Weight: 456.14
• MDL number: MFCD00134567
• UNSPSC Code: 12352005
• PubChem Substance ID: 24863854
• NACRES: NA.22

Properties

• form: slurry
• Quality Level: 200
• reaction suitability: reaction type: C-C Bond Formation
• concentration: 20 wt. % suspension in THF
• density: 1.186 g/mL at 25 °C (lit.)
• functional group: ether
• SMILES string: C1CCOC1.Br[Zn]C[Zn]C[Zn]Br
• InChI: 1S/C4H8O.2CH2.2BrH.3Zn/c1-2-4-5-3-1;;;;;;;/h1-4H2;2*1H2;2*1H;;;/q;;;;;;2*+1/p-2
• InChI key: CCTHTLJWXPUNGT-UHFFFAOYSA-L

Description

Application

Reactant for:

• Synthesis of amphidinolide T3 using a ring-closing metathesis and asymmetric dihydroxylation strategy
• Methylenation of carbonyl compounds
• Olefination reactions

Useful reagent for the methylenation of ketones and α-ketols.

Safety Information

• pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H225,H319,H335,H336,H351
• pcodes: P202 - P210 - P233 - P240 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system, Respiratory system
• supp_hazards: EUH019
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: -14.8 °F
• flash_point_c: -26 °C