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Sigma-Aldrich

Piperonylbutoxide

technical grade, 90%

Synonym(s):

2-(2-Butoxyethoxy)ethyl (6-propylpiperonyl) ether, 4,5-Methylenedioxy-2-propylbenzyldiethyleneglycol butyl ether

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About This Item

Empirical Formula (Hill Notation):
C19H30O5
CAS Number:
51-03-6
Molecular Weight:
338.44
Beilstein/REAXYS Number:
288063
EC Number:
200-076-7
MDL number:
MFCD00005842
UNSPSC Code:
12352100
PubChem Substance ID:
24857511
NACRES:
NA.22

grade

technical grade

assay

90%

refractive index

n20/D 1.498 (lit.)

bp

155 °C/0.3 mmHg (lit.)

solubility

water: slightly soluble 0.0289 g/L at 20.4 °C

density

1.059 g/mL at 25 °C (lit.)

SMILES string

CCCCOCCOCCOCc1cc2OCOc2cc1CCC

InChI

1S/C19H30O5/c1-3-5-7-20-8-9-21-10-11-22-14-17-13-19-18(23-15-24-19)12-16(17)6-4-2/h12-13H,3-11,14-15H2,1-2H3

InChI key

FIPWRIJSWJWJAI-UHFFFAOYSA-N

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General description

Piperonylbutoxide is a safe insecticide for household and field. Effect of piperonyl butoxide, a synthetic methylenedioxyphenyl inhibitor of cytochrome(s) P450, on the toxicity of organophosphate insecticides to cladoceran test species (Ceriodaphnia dubia, Daphnia magna and Daphnia pulex) has been investigated.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

supp_hazards

EUH066

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

339.8 °F - closed cup

flash_point_c

171 °C - closed cup

ppe

Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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G T Ankley et al.
Ecotoxicology and environmental safety, 21(3), 266-274 (1991-06-01)
Experiments were conducted to determine the effects of piperonyl butoxide, a synthetic methylenedioxyphenyl inhibitor of cytochrome(s) P450, on the toxicity of organophosphate insecticides to three cladoceran test species: Ceriodaphnia dubia. Daphnia magna, and Daphnia pulex. Coadministration of piperonyl butoxide effectively
Piperonyl butoxide, a new and safe insecticide for the household and field.
W E DOVE
Pests and their control, 15(9), 30-30 (1947-09-01)
Petek Piner et al.
Environmental toxicology and pharmacology, 33(3), 414-420 (2012-03-06)
The aim of this study was to investigate the toxic effects of pyrethroid pesticide lambda-cyhalothrin in the presence of piperonyl butoxide as a modulator in the liver of juvenile Oreochromis niloticus. LC(50) (96h) value of lambda-cyhalothrin was determined as 2.901μg/L
Ranil Waliwitiya et al.
Journal of medical entomology, 49(3), 614-623 (2012-06-12)
The biochemical mechanisms underlying the increased toxicity of several plant essential oils (thymol, eugenol, pulegone, terpineol, and citronellal) against fourth instar of Aedes aegypti L. when exposed simultaneously with piperonyl butoxide (PBO) were examined. Whole body biotransformational enzyme activities including
Olivier J T Briët et al.
Malaria journal, 12, 77-77 (2013-02-28)
The effectiveness of insecticide-treated nets in preventing malaria is threatened by developing resistance against pyrethroids. Little is known about how strongly this affects the effectiveness of vector control programmes. Data from experimental hut studies on the effects of long-lasting, insecticidal
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