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250619

Sigma-Aldrich

4-Amino-1-naphthalenesulfonic acid

97%

Synonym(s):

1-Naphthylamine-4-sulfonic acid, Naphthionic acid

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About This Item

Linear Formula:
H2NC10H6SO3H
CAS Number:
84-86-6
Molecular Weight:
223.25
Beilstein/REAXYS Number:
1971299
EC Number:
201-567-9
MDL number:
MFCD00004027
UNSPSC Code:
12352100
PubChem Substance ID:
24855065
NACRES:
NA.22

Quality Level

200

assay

97%

form

powder

mp

≥300 °C (lit.)

solubility

water: very slightly soluble(lit.)

SMILES string

Nc1ccc(c2ccccc12)S(O)(=O)=O

InChI

1S/C10H9NO3S/c11-9-5-6-10(15(12,13)14)8-4-2-1-3-7(8)9/h1-6H,11H2,(H,12,13,14)

InChI key

NRZRRZAVMCAKEP-UHFFFAOYSA-N

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General description

4-Amino-1-naphthalenesulfonic acid is a diazo compound. It is also known as Piria′s acid.

Application

4-Amino-1-naphthalenesulfonic acid has potent therapeutic applications. Its sodium salt has been used as non-toxic hemostatic.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCBM2476V
1356098V
1356098
05305HH
17725DE

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Sigma-Aldrich

08658

8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt

Elaheh Sajadi et al.
Bioprocess and biosystems engineering, 42(12), 2023-2034 (2019-09-07)
Based on cellulose biosynthesis pathway of Gluconacetobacterxylinus BPR2001 and E. coli Nissle 1917, bcsA and bcsB genes have been selected and bioinformatics studies done to the analyses of nucleotide and amino acid sequence alignment, stability of RNA, protein, and promotor
I Lindh et al.
Rapid communications in mass spectrometry : RCM, 8(10), 797-803 (1994-10-01)
A series of small peptides has been studied by negative-ion fast-atom bombardment mass spectrometry with collision-induced dissociation. It has been found that by derivatizing peptides with 4-aminonaphthalenesulphonic acid in a peptide linkage at the C-terminus, negative-ion formation can be enhanced
David E Lefebvre et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 110, 395-401 (2017-11-07)
The chemical amaranth (AM) is permitted as a colouring agent in a variety of foods. Safety was established based on chronic rodent studies. AM and its metabolite naphthionic acid (NA) can be absorbed through the intestine, exposing circulating immune cells
Tracing polar benzene-and naphthalenesulfonates in untreated industrial effluents and water treatment works by ion-pair chromatography-fluorescence and electrospray-mass spectrometry.
Alonso MC and Barcelo D.
Analytica Chimica Acta, 400(1), 211-231 (1999)
Circulating naphthionic acid in nonpregnant and pregnant rats after feeding amaranth.
R F Willes et al.
Toxicology and applied pharmacology, 54(2), 276-284 (1980-06-30)
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