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202355

Sigma-Aldrich

Poly(propylene glycol)

average Mn ~4,000

Synonym(s):

PPG, Poly(propylene oxide)

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About This Item

Linear Formula:
H[OCH(CH3)CH2]nOH
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

vapor density

>1 (vs air)

Quality Level

vapor pressure

<0.01 mmHg ( 20 °C)

description

functionality 1.7

mol wt

average Mn ~4,000

impurities

≤0.035% Water (Karl Fischer)

viscosity

1,300 cP(25 °C)(lit.)

hydroxyl value

28 mg KOH/g

solubility

H2O: <0.01 % (w/w) at 25 °C

density

1.004 g/mL at 25 °C

SMILES string

CC(O)CO

InChI

1S/C6H14O3/c1-5(8)4-9-6(2)3-7/h5-8H,3-4H2,1-2H3

InChI key

DUFKCOQISQKSAV-UHFFFAOYSA-N

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General description

Poly(propylene glycol) (PPG) is a hydrophobic polyether that is widely used in various biomedical areas such as preparation of biocompatible polyurethanes and lubricious coatings on absorbable sutures.

Application

Poly(propylene glycol) can be used:
  • As a precursor to synthesize biodegradable poly(ether-ester) networks via UV photopolymerization.
  • As a stabilizing agent in the preparation of metal nanoparticles such as gold nanoparticles.
  • As a starting material to prepare silane-terminatedpoly(urethane-urea)s (SPUR) polymers.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

445.0 °F - closed cup

flash_point_c

229.44 °C - closed cup

ppe

Eyeshields, Gloves


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Mohammed Taghi Zafarani-Moattar et al.
Biotechnology progress, 28(1), 146-156 (2011-09-29)
In this work, we proposed a novel aqueous biphasic system (ABS) composed of polypropylene glycol P400 (PPG P400) and hydrophilic ionic liquids (IL), 1-alkyl-3-methylimidazolium bromide (alkyl = ethyl or butyl), forming an upper polymer-rich phase and a lower IL-rich phase
Celeste R Brennecka et al.
World neurosurgery, 78(5), 469-480 (2011-11-29)
Current treatments for cerebral aneurysms are far from ideal. Platinum coils are prone to compaction, and currently used liquid embolics are delivered with angiotoxic agents. This work presents initial in vivo studies of a novel liquid-to-solid gelling polymer system (PPODA-QT)
John Texter et al.
Macromolecular rapid communications, 33(1), 69-74 (2011-12-03)
The controlled atom transfer radical polymerization of an ionic liquid, 1-(11-acryloylundecyl)-3-methyl imidazolium bromide (ILBr), from both ends of a telechelic poly(propylene oxide) (PPO) macroinitiator, end-functionalized with bromoisobutyryloyl is reported. The resulting highly water-soluble triblock, poly(ILBr-b-PO-b-ILBr) is multistimuli responsive. This new
Flávia Chiva Carvalho et al.
Journal of biomedical nanotechnology, 8(2), 280-289 (2012-04-21)
In the last few decades, nanotechnology has led to an advance in the development of topical drug delivery. Nanostructured drug delivery systems enable the compartmentalization of drugs in restricted environments, modifying the release profile and maintaining the required drug concentration
R De Lisi et al.
Physical chemistry chemical physics : PCCP, 13(27), 12571-12577 (2011-06-15)
The study highlighted the main forces driving the formation of hydroxypropyl-cyclodextrins (HP-CDs) + poly(propylene) glycol 725 g mol(-1) inclusion complexes. The temperature parameter was chosen as the variable to modulate the hydrophobicity of the polymer, and consequently ITC experiments as

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