191523
3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane
98%
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assay
98%
bp
108-110 °C/2 mmHg (lit.)
mp
43-46 °C (lit.)
density
1.251 g/mL at 25 °C (lit.)
SMILES string
C=CC1OCC2(CO1)COC(OC2)C=C
InChI
1S/C11H16O4/c1-3-9-12-5-11(6-13-9)7-14-10(4-2)15-8-11/h3-4,9-10H,1-2,5-8H2
InChI key
OOXMQACSWCZQLX-UHFFFAOYSA-N
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Application
3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane is an acetal-type crosslinking agent comonomer and has been used:
- in radical emulsion copolymerization of 2-hydroxyethyl methacrylate
- as cross-linking agent in the synthesis of acid-degradable core-crosslinked micelles
- in the synthesis of new biocompatible copolymer for loading the indomethacin as drug model
Storage Class
11 - Combustible Solids
wgk_germany
WGK 2
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Upon the emulsion polymerization of 2-hydroxyethyl methacrylate with 3, 9-divinyl-2, 4, 8, 10-tetraoxaspiro [5.5]-undecane.
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Journal of materials science. Materials in medicine, 23(5), 1211-1223 (2012-03-15)
The study presents the possibility to use the 2-hydroxyethyl methacrylate--HEMA copolymer with a comonomer with spiroacetal moiety, 3,9-divinyl-2,4,8,10-tetraoxaspiro[5.5]-undecane)-U, as polymer network for loading the indomethacin--INN as drug model, and also, the controlled release evaluation of the prepared bioactive system. The
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