113727
Norphenylephrine hydrochloride
98%
Synonym(s):
α-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride, 3,α-Dihydroxyphenethylamine hydrochloride, Norfenefrine hydrochloride
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About This Item
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Quality Level
assay
98%
form
solid
mp
162-164 °C (lit.)
functional group
amine
hydroxyl
SMILES string
Cl.NCC(O)c1cccc(O)c1
InChI
1S/C8H11NO2.ClH/c9-5-8(11)6-2-1-3-7(10)4-6;/h1-4,8,10-11H,5,9H2;1H
InChI key
OWMFSWZUAWKDRR-UHFFFAOYSA-N
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Application
Norphenylephrine hydrochloride was used in the study of the effects of phenylephrine on the isolated heart of rabbit.
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Journal of molecular medicine (Berlin, Germany), 75(11-12), 849-859 (1998-01-15)
The effect of beta- and alpha-adrenergic stimulation on cardiovascular function and development of cardiac hypertrophy was studied in rats by measuring the heart weight/body weight and cardiac RNA/DNA ratios. Beta-receptor stimulation with isoproterenol over 3 days induced an increase in
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This study presents a four-channel electrophoresis chip platform, featuring double-cross hydrostatic sample injection, for rapid chiral selector screening. This platform needs only five electrodes to drive microchip electrophoresis in four separate channels for screening four chiral selectors at a time.
British journal of pharmacology, 97(2), 483-489 (1989-06-01)
1. The effects on food intake in rats of injection of m- and p-octopamine into the paraventricular nucleus (PVN) of the hypothalamus were examined, and compared to the effects of noradrenaline (NA). 2. m-Octopamine injected into the PVN induced a
British journal of pharmacology, 48(1), 132-138 (1973-05-01)
1. In the driven rabbit left atrium alpha-adrenoceptors mediate the inotropic effect of phenylephrine and the prolongation of functional refractory period by sympathomimetic amines.2. These receptors are highly sensitive to blockade by phentolamine and phenoxybenzamine.3. Prolongation of functional refractory period
Journal of neurochemistry, 53(1), 149-154 (1989-07-01)
Functions of octopamine in the mammalian brain are still not well known. An important aspect of this problem is the relationship between octopamines and catecholamines. Previous data have shown that their respective ontogenic evolutions are not parallel. Do the changes
Chromatograms
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