PARP1
poly (ADP-ribose) polymerase 1
Synonyms:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Species:
Human PARP1 (142), Mouse Parp1 (11545), Rat Parp1 (25591), Thale Cress PARP1 (817690), Zebrafish parp1 (560788), chicken PARP1 (396199), dog PARP1 (490385), domestic cat PARP1 (101081434), Horse PARP1 (100058523), cow PARP1 (286764) ...More
UniProtKB ID:
Gene ID:
- Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
- Mouse(11545) poly (ADP-ribose) polymerase family, member 1
- Rat(25591) poly (ADP-ribose) polymerase 1
- Thale Cress(817690) poly [ADP-ribose] polymerase 2
- Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
- chicken(396199) poly (ADP-ribose) polymerase 1
- dog(490385) poly (ADP-ribose) polymerase 1
- domestic cat(101081434) poly (ADP-ribose) polymerase 1
- Horse(100058523) poly (ADP-ribose) polymerase 1
- cow(286764) poly (ADP-ribose) polymerase 1
- domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
- naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
- sheep(100135697) poly (ADP-ribose) polymerase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PARP-1 Antibody, clone 12N17 Antibody, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-PARP antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
microarray
western blot
microarray
western blot
Anti-Poly ADP-ribose Antibody, clone 10H, clone 10H, from mouse,
Species Reactivity
human
Application
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Rabbit anti-PARP1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human
Application
western blot
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
PARP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Species
human
Monoclonal Anti-PARP1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2209, purified immunoglobulin, buffered aqueous glycerol solution,
Species
human
Monoclonal Anti-PARP1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2220, purified immunoglobulin, buffered aqueous glycerol solution,
Species
human