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MYC

v-myc avian myelocytomatosis viral oncogene homolog

Synonyms:
MRTL, MYCC, bHLHe39, c-Myc
Species:
Human MYC (4609), Mouse Myc (17869), Rat Myc (24577), chicken MYC (420332), dog MYC (403924), domestic cat MYC (100379628), cow MYC (511077), domestic guinea pig Myc (100724557), Domestic Rabbit MYC (100327265), sheep MYC (443447)
UniProtKB ID:
P01106, A8WFE7, P01107, Q14026
Gene ID:
  • Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17869) myelocytomatosis oncogene
  • Rat(24577) myelocytomatosis oncogene
  • chicken(420332) v-myc myelocytomatosis viral oncogene homolog
  • dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
  • cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)
  • Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
  • sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)

Custom & Knockdown Gene Products

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
RAB1379
Human c-Myc ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB4702005
Monoclonal Anti-c-Myc tag Biotin produced in mouse, ,
Species Reactivity
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB4503660
Anti-MYC antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
05-724
Anti-Myc Tag Antibody, clone 4A6, clone 4A6, Upstate®, from mouse,
Species Reactivity
human
Application
ChIP
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
SAB2108476
Anti-MYC, affinity isolated antibody,
Species Reactivity
guinea pig, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
16-219
Anti-Myc Tag Antibody, clone 4A6, agarose conjugate, clone 4A6, Upstate®, from mouse,
Species Reactivity
human
Application
immunoprecipitation (IP)

Proteins

Product Number
Description
Species
SRP2089
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EHU021051
MISSION® esiRNA, targeting human MYC,
Species
human
EMU075291
MISSION® esiRNA, targeting mouse Myc,
Species
mouse