CTTN
cortactin
Synonyms:
EMS1
Species:
Human CTTN (2017), Mouse Cttn (13043), Rat Cttn (60465), sheep CTTN (101117549), Domestic Rabbit CTTN (100337860), naked mole-rat Cttn (101705176), domestic guinea pig Cttn (100731735), Zebrafish cttn (445561), cow CTTN (506939), Horse CTTN (100147634) ...More
UniProtKB ID:
Gene ID:
- Human(2017) Summary: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]
- Mouse(13043) cortactin
- Rat(60465) cortactin
- sheep(101117549) cortactin
- Domestic Rabbit(100337860) cortactin
- naked mole-rat(101705176) cortactin
- domestic guinea pig(100731735) cortactin
- Zebrafish(445561) cortactin
- cow(506939) cortactin
- Horse(100147634) cortactin
- domestic cat(101088615) cortactin
- dog(610283) cortactin
- chicken(396455) cortactin
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Cortactin (p80/85) Antibody, clone 5G3.2, clone 5G3.2, from mouse,
Species Reactivity
human, mouse
Application
western blot
Anti-phospho-Cortactin (pTyr421) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-phospho-Cortactin (pTyr421) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
mouse
Application
immunocytochemistry
western blot
western blot
Anti-Cortactin/EMS1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, rat
Application
ELISA
western blot
western blot
Anti-Cortactin Antibody, phospho-specific [Tyr466], Chemicon®, from rabbit,
Species Reactivity
mouse
Application
western blot