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MilliporeSigma

ACTA1

actin, alpha 1, skeletal muscle

Synonyms:
ACTA, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3
Species:
UniProtKB ID:
Gene ID:
  • Human(58) Summary: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]
  • Mouse(11459) actin, alpha 1, skeletal muscle
  • Rat(29437) actin, alpha 1, skeletal muscle
  • chicken(421534) actin, alpha 1, skeletal muscle
  • Horse(100065454) actin, alpha 1, skeletal muscle
  • cow(281592) actin, alpha 1, skeletal muscle
  • domestic cat(101095439) actin, alpha 1, skeletal muscle
  • dog(488984) actin, alpha 1, skeletal muscle
  • naked mole-rat(101721383) actin, alpha 1, skeletal muscle
  • domestic guinea pig(100716933) actin, alpha 1, skeletal muscle
  • sheep(101107662) actin, alpha 1, skeletal muscle

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Actin-pan antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Actin Antibody, clone C4, Alexa Fluor 555 Conjugate, clone C4, from mouse, ALEXA FLUOR 647,
Species Reactivity
chicken, human
Application
immunocytochemistry
Anti-α-Actin Mouse mAb (1A4), liquid, clone 1A4, Calbiochem®,
Species Reactivity
baboon, human, rabbit
Application
Anti-Actin Antibody, clone 2G2, clone 2G2, from mouse,
Species Reactivity
chicken, frog, human, monkey, mouse, rabbit, rat
Application
immunocytochemistry
western blot
Anti-Actin Antibody, clone C4, Alexa Fluor 647 conjugate, clone C4, from mouse, ALEXA FLUOR 647,
Species Reactivity
chicken, human
Application
immunocytochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACTA1,
Species
human