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ACSL4

acyl-CoA synthetase long-chain family member 4

Synonyms:
ACS4, FACL4, LACS4, MRX63, MRX68
Species:
UniProtKB ID:
Gene ID:
  • Human(2182) Summary: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(50790) acyl-CoA synthetase long-chain family member 4
  • Rat(113976) acyl-CoA synthetase long-chain family member 4
  • chicken(422345) acyl-CoA synthetase long-chain family member 4
  • cow(536628) acyl-CoA synthetase long-chain family member 4
  • Horse(100054459) acyl-CoA synthetase long-chain family member 4
  • domestic cat(101090925) acyl-CoA synthetase long-chain family member 4
  • dog(481018) acyl-CoA synthetase long-chain family member 4
  • sheep(101111781) acyl-CoA synthetase long-chain family member 4
  • Domestic Rabbit(100342485) acyl-CoA synthetase long-chain family member 4
  • naked mole-rat(101717258) acyl-CoA synthetase long-chain family member 4
  • domestic guinea pig(100722621) acyl-CoA synthetase long-chain family member 4

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ACSL4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-ACSL4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ACSL4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ACSL4 (C-terminal) antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACSL4,
Species
human
MISSION® esiRNA, targeting mouse Acsl4,
Species
mouse