- An efficient base-free N-arylation of imidazoles and amines with arylboronic acids using copper-exchanged fluorapatite.
An efficient base-free N-arylation of imidazoles and amines with arylboronic acids using copper-exchanged fluorapatite.
The Journal of organic chemistry (2006-12-02)
M Lakshmi Kantam, Gopaldasu T Venkanna, Chidara Sridhar, Bojja Sreedhar, Boyapati M Choudary
PMID17137388
ABSTRAKT
N-Arylation of imidazoles and amines with arylboronic acids was accomplished with copper-exchanged fluorapatite (CuFAP) in methanol at room temperature. The products N-arylimidazoles and N-arylamines were isolated in good to excellent yields. A variety of arylboronic acids were converted to the corresponding N-arylimidazoles and N-arylamines, demonstrating the versatility of the reaction.