- Efficient scavenging of Ph3P and Ph3P=O with high-loading merrifield resin.
Efficient scavenging of Ph3P and Ph3P=O with high-loading merrifield resin.
Organic letters (2001-06-19)
B H Lipshutz, P A Blomgren
PMID11405732
ABSTRAKT
[see reaction]. A simple, highly effective method for removing triphenylphosphine and/or triphenylphosphine oxide from reaction mixtures is described. Commercially available high-loading chloromethylated polystyrene 1, modified in situ with NaI, acts as a scavenger resin. Several coupling reactions catalyzed by Pd(0) or Ni(0) which require the removal of triphenylphosphine are tested.
MATERIAŁY