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T3955

Sigma-Aldrich

TNP

≥95% (HPLC)

Synonim(y):

N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

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About This Item

Wzór empiryczny (zapis Hilla):
C20H16F3N7O2
Numer CAS:
519178-28-0
Masa cząsteczkowa:
443.38
Numer MDL:
MFCD16875436
Kod UNSPSC:
12352200
Identyfikator substancji w PubChem:
329826781
NACRES:
NA.77

Poziom jakości

100

Próba

≥95% (HPLC)

Postać

powder

warunki przechowywania

protect from light

kolor

yellow

rozpuszczalność

DMSO: ≥10 mg/mL

inicjator

Novartis

temp. przechowywania

2-8°C

ciąg SMILES

[O-][N+](=O)c1ccc(CNc2nc(NCc3cccc(c3)C(F)(F)F)nc4[nH]cnc24)cc1

InChI

1S/C20H16F3N7O2/c21-20(22,23)14-3-1-2-13(8-14)10-25-19-28-17(16-18(29-19)27-11-26-16)24-9-12-4-6-15(7-5-12)30(31)32/h1-8,11H,9-10H2,(H3,24,25,26,27,28,29)

Klucz InChI

DDSBPUYZPWNNGH-UHFFFAOYSA-N

Działania biochem./fizjol.

TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.

Cechy i korzyści

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Uwaga dotycząca przygotowania

TNP is soluble in DMSO at a concentration that is greater than or equal to 10 mg/ml.
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Certyfikaty analizy (CoA)

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