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T2402
Anti-Mouse IgG (whole molecule)−TRITC antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
Synonim(y):
Rabbit Anti-Mouse IgG (whole molecule)−Tetramethylrhodamine isothiocyanate
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About This Item
Polecane produkty
pochodzenie biologiczne
rabbit
Poziom jakości
białko sprzężone
TRITC conjugate
forma przeciwciała
IgG fraction of antiserum
rodzaj przeciwciała
secondary antibodies
klon
polyclonal
Formularz
buffered aqueous solution
warunki przechowywania
protect from light
metody
direct immunofluorescence: 1:64
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200
temp. przechowywania
−20°C
docelowa modyfikacja potranslacyjna
unmodified
Opis ogólny
Immunoglobulins (Igs) belongs immunoglobulin super-family. There are five different types of Immunoglobulins. Each immunoglobulin has two heavy (H) and two light (L), held together by disulphide linkages. Each light comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region. IgG is abundant immunoglobulin in human serum. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4.
Specyficzność
Anti-Mouse IgG (whole molecule)-TRITC antibody is specific for mouse IgG.
Immunogen
Normal mouse serum
Zastosowanie
Anti-Mouse IgG (whole molecule)-TRITC antibody is suitable for use in direct immunofluorescence (1:64), immunohistochemistry (1:200 dilution in formalin-fixed, paraffin-embedded sections), Ouchterlony double diffusion and electrophoresis techniques.
Działania biochem./fizjol.
Digestion of IgG by papain results in generation of fragment antigen binding (Fab) comprising one complete L chain and a variable and CH1 region of H chain. Pepsin digestion of IgG results in fragment crystallizable (fc), comprises the H chain constant region.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice .
Postać fizyczna
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
nwg
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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