T0910

Thioredoxin from Escherichia coli

recombinant, expressed in E. coli, essentially salt-free, lyophilized powder, ≥3 units/mg protein

• Numer CAS: 52500-60-4
• Numer MDL: MFCD00132423
• Kod UNSPSC: 12352200
• NACRES: NA.32

Właściwości

• pochodzenie biologiczne: Escherichia coli
• Poziom jakości: 200
• rekombinowane: expressed in E. coli
• Próba: ≥90% (SDS-PAGE)
• Postać: essentially salt-free, lyophilized powder
• aktywność właściwa: ≥3 units/mg protein
• masa cząsteczkowa: 11.7 kDa
• metody: activity assay: suitable
• rozpuszczalność: water: 1.90-2.10 mg/mL, clear, colorless
• numer dostępu Protein ID: M26133
• numer dostępu UniProt: P0AA25
• Zastosowanie: cell analysis
• temp. przechowywania: −20°C
• informacje o genach: Escherichia coli K12 ... trxA(948289)

Opis

Opis ogólny

Research area: Cell Signaling

Thioredoxin from Escherichia coli is a monomeric, globular protein. It has a central β-sheet surrounded by α-helices.

Zastosowanie

Thioredoxin from Escherichia coli has been used in thioredoxin reductase assay, peroxidase-coupled thioredoxin system assay and peroxiredoxin assay. It has also been used to study its effects on photoreceptor death in a mouse model of retinitis pigmentosa (RP) and its potential to modify retinal oxidative stress, glial changes, and vascular changes during the progression of the disease.

Działania biochem./fizjol.

Thioredoxin from Escherichia coli catalyzes REDOX reactions and has a role in various biological processes. It modulates the structure and activity of many proteins. The enzyme thioredoxin reductase catalyzes the reduction of thioredoxin. Thioredoxin also has a role in oxidative stress response.Thioredoxin, known as both adult T cell leukemia-derived factor (ADF) and a cellular redox enzyme, functions as a cytokine or chemokine, facilitating cell-to-cell communication. Additionally, it plays a role in regulating cell growth and apoptosis.

Mediates the reduction of disulfide bonds in proteins.

Inne uwagi

GenBank^® Accession Number M26133.

Definicja jednostki

One unit will cause a ΔA₆₅₀ of 1.0 in 1 min at 25 °C in the insulin reduction assay.

Informacje prawne

GenBank is a registered trademark of United States Department of Health and Human Services

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)