SRP0699

STK9 Protein

recombinant

• Kod UNSPSC: 12352202

Właściwości

• rekombinowane: expressed in baculovirus infected Sf9 cells
• Próba: 70-95% (SDS-PAGE)
• Postać: frozen liquid
• masa cząsteczkowa: ~84 kDa
• stężenie: 0.1 μg/μL
• nr dostępu: NM_003159
• Warunki transportu: dry ice
• temp. przechowywania: −70°C
• informacje o genach: human ... STK9(6792)

Opis

Zastosowanie

Useful for Western blot.

Działania biochem./fizjol.

Recombinant human STK9 (CDKL5) (1-498) was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. STK9 or CDKL5 is a member of Ser/Thr protein kinase family which has protein kinase activity and is associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). STK9 can control nuclear speckle morphology by regulating the phosphorylation state of splicing regulatory proteins, and may be involved indirectly in pre-mRNA processing, by controlling splicing factor dynamics ⁽¹⁾. The mutations in the STK9 is a major cause of infantile spasms and early epileptic seizures in female patients, and of a later intractable seizure disorder ⁽²⁾.

Rekonstytucja

Formulated in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

Przechowywanie i stabilność

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable