SMB01048

Uzarin

≥90% (LC/MS-ELSD)

• Synonim(y): (3beta,5alpha)-3-((6-O-beta-D -glucopyranosyl-beta-D -glucopyranosyl)oxy)-14-hydroxycard-20(22)-enolide, Uzarigenin 3-β-sophoroside
• Wzór empiryczny (zapis Hilla): C₃₅H₅₄O₁₄
• Numer CAS: 20231-81-6
• Masa cząsteczkowa: 698.79
• Kod UNSPSC: 12352205

Właściwości

• Próba: ≥90% (LC/MS-ELSD)
• Postać: solid
• Zastosowanie: metabolomics; vitamins, nutraceuticals, and natural products
• temp. przechowywania: −20°C
• InChI: 1S/C35H54O14/c1-33-8-5-18(46-32-30(28(42)26(40)23(14-37)48-32)49-31-29(43)27(41)25(39)22(13-36)47-31)12-17(33)3-4-21-20(33)6-9-34(2)19(7-10-35(21,34)44)16-11-24(38)45-15-16/h11,17-23,25-32,36-37,39-44H,3-10,12-15H2,1-2H3/t17-,18-,19+,20-,21+,22+,23+,25+,26+,27-,28-,29+,30+,31-,32+,33-,34+,35-/m0/s1
• Klucz InChI: RIPMDUQTRRLJTE-QHYHXNCWSA-N

Opis

Opis ogólny

Uzarin, also known as Uzarigenin, is a cardenolide glycoside commonly found in plants such as Xysmalobium undulatum, Nerium oleander, Asclepias fruticosa, and Calotropis procera. Existing research suggests that this plant-derived metabolite exerts multiple biological properties, including antidiarrheal, antiviral and anticancer.

Zastosowanie

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Działania biochem./fizjol.

According to the existing research, Uzarin plays potential role as an inhibitor of the SARS-CoV-2 receptor binding domain and SARS-CoV-2 RNA-dependent polymerase, as indicated by molecular docking and dynamics studies.

Cechy i korzyści

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Inne uwagi

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H300 + H330 - H373
• Zwroty wskazujące środki ostrożności: P260 - P264 - P270 - P271 - P304 + P340 + P310 - P314
• Klasyfikacja zagrożeń: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 2
• Kod klasy składowania: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable