SAB4300083
Anti-phospho-GRIN1 (pSer896) antibody produced in rabbit
affinity isolated antibody
Synonim(y):
Anti-NMDA1 antibody produced in rabbit, Anti-NMDAR1 antibody produced in rabbit, Anti-NR1 antibody produced in rabbit, Anti-glutamate receptor, ionotropic, N-methyl D-aspartate 1 antibody produced in rabbit
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About This Item
pochodzenie biologiczne
rabbit
Poziom jakości
białko sprzężone
unconjugated
forma przeciwciała
affinity isolated antibody
rodzaj przeciwciała
primary antibodies
klon
polyclonal
Postać
buffered aqueous solution
masa cząsteczkowa
~120 kDa
reaktywność gatunkowa
human, mouse, rat
stężenie
1 mg/mL
metody
western blot: 1:500-1:1000
izotyp
IgG
sekwencja immunogenna
(R-R-SP-S-K)
numer dostępu NCBI
numer dostępu UniProt
Warunki transportu
wet ice
temp. przechowywania
−20°C
docelowa modyfikacja potranslacyjna
phosphorylation (pSer896)
informacje o genach
human ... GRIN1(2902)
Powiązane kategorie
Immunogen
Peptide sequence around phosphorylation site of serine 896 (R-R-S(p)-S-K), according to the protein GRIN1.
Cechy i korzyści
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Opis wartości docelowych
NMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation (LTP) and depression (LTD). NMDA receptors have a critical role in excitatory synaptic transmission and plasticity in the CNS. They govern a rangeof physiological conditions including neurological disorders caused by excitotoxic neuronal injury, psychiatric disorders and neuropathic pain syndromes.
Postać fizyczna
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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