S7656
Anti-Staphylococcal Enterotoxin A antibody produced in rabbit
whole antiserum
Synonim(y):
Anti-Ent A
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About This Item
Polecane produkty
pochodzenie biologiczne
rabbit
białko sprzężone
unconjugated
forma przeciwciała
whole antiserum
rodzaj przeciwciała
primary antibodies
klon
polyclonal
zawiera
15 mM sodium azide
reaktywność gatunkowa
Staphylococcus aureus
metody
dot blot: 1:20,000 using using purified Staphyloccal Enterotoxin A immobilized on nitrocellulose membranes (protein concentation: 50 ng/dot).
indirect ELISA: 1:20,000 using using Staphylococcal enterotoxin A
Warunki transportu
dry ice
temp. przechowywania
−20°C
docelowa modyfikacja potranslacyjna
unmodified
Powiązane kategorie
Opis ogólny
The antibody is positive against Staphylococcal enterotoxin A, negative versus Staphylococcal enterotoxin B, Cholera toxin, and Pseudomonas exotoxin A (protein concentration: 50-500 ng/dot). The antibody has not been tested for neutralization potency against active Staphylococcal enterotoxin A.
Immunogen
enterotoxin A from Staphylococcus aureus.
Zastosowanie
Anti-Staphylococcal Enterotoxin A antibody has been used in western blotting, and enterotoxin A detection by ELISA (enzyme-linked immunosorbent assay).
Anti-Staphylococcal Enterotoxin A antibody produced in rabbit was used as a control to SEA-conjugated MUSE11 antibody produced in xenografted SCID mice.
Działania biochem./fizjol.
Staphylococcal enterotoxin A (SEA) from Staphylococcal aureus is leading agent that causes of food poisoning. A concentration of as little as 0.5 mg/ml is sufficient to result in nausea, vomiting, diarrhea and cramps. It stimulates the cell proliferation of peripheral lymphocytes, induces the production of interferons and is important for gut immunity against S. aureus infections.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 1
Certyfikaty analizy (CoA)
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Cancer research, 58(13), 2838-2843 (1998-07-14)
To reinforce cytotoxic activity and the targeting ability of lymphokine-activated killer cells with a T-cell phenotype (T-LAK) for adoptive immunotherapy against human bile duct carcinoma (BDC), staphylococcal enterotoxin A (SEA) was conjugated chemically with MUSE11 monoclonal antibody (MUSE11 mAb), directed
N Sakurai et al.
Biochemical and biophysical research communications, 256(1), 223-230 (1999-03-06)
A SEA-antibody single chain Fv (SEA-scFv) fusion protein was produced by bacterial expression system in this study. SEA-scFv has both staphylococcal enterotoxin A (SEA) effects and antibody activity directed at the epithelial mucin core protein MUC1, a cancer associated antigen.
A mutated superantigen SEA D227A fusion diabody specific to MUC1 and CD3 in targeted cancer immunotherapy for bile duct carcinoma
Takemura S I, et al.
Cancer Immunology, Immunotherapy, 51(1), 33-44 (2002)
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Cancer immunology, immunotherapy : CII, 51(1), 33-44 (2002-02-15)
In cancer immunotherapy research, many bispecific antibodies (BsAbs) have been developed for directing T cells toward tumor cells. Recent advances in genetic engineering have made it possible to prepare immunoglobulin fragments consisting of variable domains using bacterial expression systems. Therefore
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