P7036

Parathyroid hormone human

≥92% (HPLC), powder

• Synonim(y): PTH, Parathormone
• Wzór empiryczny (zapis Hilla): C₄₀₈H₆₇₄N₁₂₆O₁₂₆S₂
• Numer CAS: 68893-82-3
• Masa cząsteczkowa: 9424.62
• Numer MDL: MFCD00081830
• Kod UNSPSC: 51111800
• NACRES: NA.32
• pochodzenie biologiczne: synthetic (organic)
• Formularz: powder
• Próba: ≥92% (HPLC)

Właściwości

• pochodzenie biologiczne: synthetic (organic)
• Poziom jakości: 200
• sterylność: non-sterile
• Próba: ≥92% (HPLC)
• Formularz: powder
• skład: Peptide content, ≥70%
• rozpuszczalność: water: 1 mg/mL, clear, colorless
• numer dostępu UniProt: P01270
• Warunki transportu: ambient
• temp. przechowywania: −20°C
• informacje o genach: human ... PTH(5741)

Opis

Amino Acid Sequence

Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asn-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln

Opis ogólny

Parathyroid hormone (PTH) is a circulating hormone secreted from the parathyroid gland. This hormone is synthesized as a pre-pro hormone. PTH is composed of binding regions that have a high affinity to a receptor and functional domains that interact with the receptors to initiate an intracellular signaling cascade.

Zastosowanie

Parathyroid hormone human has been used to incubate mature human adipocytes.

Działania biochem./fizjol.

Parathyroid hormone (PTH) exerts its effects on bone and kidney cells. This hormone plays a role in calcium homeostasis. PTH is secreted from the chief cells of the parathyroid gland in response to low extracellular calcium levels or higher levels of extracellular phosphate. PTH deficiency or excess PTH are associated with hypoparathyroidism and hyperparathyroidism, respectively.

Komponenty

Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asn-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable