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MAK051

Sigma-Aldrich

Aconitase Activity Assay Kit

sufficient for 100 colorimetric tests

Synonim(y):

Aconitase Enzyme Activity Kit

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About This Item

Kod UNSPSC:
12161503
NACRES:
NA.84

zastosowanie

sufficient for 100 colorimetric tests

metoda wykrywania

colorimetric

powiązane choroby

neurological disorders; cardiovascular diseases; cancer

temp. przechowywania

2-8°C

informacje o genach

human ... ACO1(48) , ACO2(50)
mouse ... ACO1(11428) , ACO2(11429)
rat ... ACO1(50655) , ACO2(79250)

Opis ogólny

The aconitases are a family of iron-sulfur containing enzymes that catalyzes the isomerization of citrate to isocitrate. Two aconitases, encoded by different genes, have been identified in eukaryotes. Aconitase 1 (ACO1, c-aconitase) is a cytosolic enzyme while Aconitase 2 (ACO2, m-aconitase) is a mitochondrial enzyme that functions in the tricarboxylic acid cycle. Aconitases are reversibly inactivated by oxidative stress, and aconitase activity in cells and tissues has been used as a biomarker for oxidative damage.

Zastosowanie

Aconitase Activity Assay Kit has been used to measure the activity of cytosolic and mitochondrial aconitase enzyme.

Cechy i korzyści

Compatible with high-throughput handling systems.

Przydatność

Suitable for the measurement of aconitase activity in biological samples including tissue and cells

Zasada

The Aconitase Activity Assay kit provides a simple and direct procedure for measuring Aconitase activity in a variety of samples. Aconitase activity is determined in a coupled enzyme reaction in which citrate is converted to isocitrate by aconitase. This results in a colorimetric (450 nm) product proportional to the enzymatic activity present. One unit of aconitase is the amount of enzyme that will isomerize 1.0 μmole of citrate from isocitrate per minute at pH 7.4 at 25 °C.
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zastąpiony przez

Numer produktu
Opis
Cennik

Piktogramy

Health hazardCorrosion
GHS08,GHS05

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H314,H334

Klasyfikacja zagrożeń

Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B

Kod klasy składowania

8A - Combustible corrosive hazardous materials

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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