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Key Documents

M9434

Sigma-Aldrich

Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat

clone 14, tissue culture supernatant

Synonim(y):

Anti-MBP

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About This Item

Numer MDL:
Kod UNSPSC:
12352203

pochodzenie biologiczne

rat

Poziom jakości

białko sprzężone

unconjugated

forma przeciwciała

tissue culture supernatant

rodzaj przeciwciała

primary antibodies

klon

14, monoclonal

zawiera

0.09% sodium azide

reaktywność gatunkowa

horse, chicken, human

metody

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

izotyp

IgG

numer dostępu UniProt

Warunki transportu

dry ice

temp. przechowywania

−20°C

docelowa modyfikacja potranslacyjna

unmodified

informacje o genach

human ... MBP(4155)

Opis ogólny

Myelin basic protein (MBP) is part of the myelin sheath and is a calcium-dependent protein. It has six isoforms and the gene encoding it is localized on human chromosome 18q23.

Specyficzność

Recognizes amino acids 36-50 of myelin basic protein.

Immunogen

bovine myelin basic protein.

Działania biochem./fizjol.

Myelin basic protein (MBP) associates with calmodulin and has been identified as an auto-antigen in multiple sclerosis (MS). It also inhibits the assembly of amyloid-β protein.

Uwaga dotycząca przygotowania

Generated by somatic cell hybridization of NS0 myeloma cells with spleen cells from an outbred rat immunized with bovine myelin basic protein.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

10 - Combustible liquids


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