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Merck

I5281

SAFC

L-Isoleucine

Produkcja farmaceutyczna

Synonim(y):

(2S,3S)-2-Amino-3-methylpentanoic acid

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About This Item

Wzór liniowy:
C2H5CH(CH3)CH(NH2)CO2H
Numer CAS:
Masa cząsteczkowa:
131.17
Beilstein:
1721792
Numer WE:
Numer MDL:
Kod UNSPSC:
12352209
eCl@ss:
32160406
NACRES:
NA.26

pochodzenie biologiczne

non-animal source

Poziom jakości

Próba

≥98.5%

Formularz

crystalline powder

metody

cell culture | mammalian: suitable

zanieczyszczenia

endotoxin, heavy metals, residual solvents, tested

mp

288 °C (dec.) (lit.)

rozpuszczalność

1 M HCl: 50 mg/mL

Zastosowanie

pharmaceutical (small molecule)

obecność zanieczyszczeń

cytotoxicity, tested

ciąg SMILES

CC[C@H](C)[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1

Klucz InChI

AGPKZVBTJJNPAG-WHFBIAKZSA-N

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Opis ogólny

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Zastosowanie

L-Isoleucine is an essential amino acid. It can be biosynthesized from threonine or through fermentation of carbohydrates. The amino acid L-isoleucine is an isomer of L-Leucine, differing in the position of the side chain. It is also considered to be a branched chain amino acid, along with L-Leucine and L-Valine, which are sources of fuel and/or transport during cell development. It is used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Informacje prawne

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)


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The Journal of nutrition, 136(1 Suppl), 269S-273S (2005-12-21)
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Proceedings of the National Academy of Sciences of the United States of America, 111(14), E1334-E1343 (2014-04-08)
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