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Isocitric Dehydrogenase (NADP) from porcine heart
Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein
Synonim(y):
threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH, IDH
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About This Item
Polecane produkty
typ
Type IV
Poziom jakości
Formularz
buffered aqueous glycerol solution
jakość
≤ 0.2% of main activity is obtained with NAD as cofactor.
aktywność właściwa
3-20 units/mg protein
skład
Protein biuret
Warunki transportu
wet ice
temp. przechowywania
2-8°C
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Zastosowanie
Isocitric dehydrogenase (IDH) has been used:
- for in vitro activity assay to study the effects of thorium on citric acid cycle enzymes in the mitochondrial respiration pathway
- as a standard to measure the impact of temperature on nicotinamide diphosphate (NADP)-IDH activity
- in isocitrate assay
Działania biochem./fizjol.
Isocitrate dehydrogenase (IDH) is a homodimeric enzyme and participates in several processes such as adapting to hypoxia, histone demethylation, and DNA modification. This enzyme has three isoforms like IDH1, IDH2, and IDH3.
Definicja jednostki
One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37 °C.
Postać fizyczna
Solution in 50% glycerol in EDTA buffer salts, pH 6.0
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Inhibitor
Numer produktu
Opis
Cennik
Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Środki ochrony indywidualnej
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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