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G5421
Monoclonal Anti-Granulocyte Colony Stimulating Factor antibody produced in rat
clone 67604, purified immunoglobulin, lyophilized powder
Synonim(y):
Anti-Csf3, Anti-Csfg, Anti-G-CSF, Anti-MGI-IG
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
About This Item
Kod UNSPSC:
51111800
NACRES:
NA.41
Polecane produkty
pochodzenie biologiczne
rat
Poziom jakości
białko sprzężone
unconjugated
forma przeciwciała
purified immunoglobulin
rodzaj przeciwciała
primary antibodies
klon
67604, monoclonal
Postać
lyophilized powder
reaktywność gatunkowa
mouse
metody
capture ELISA: 2-8 μg/mL
neutralization: suitable
western blot: 1-2 μg/mL
izotyp
IgG1
numer dostępu UniProt
temp. przechowywania
−20°C
informacje o genach
mouse ... Csf3(12985)
Powiązane kategorie
Opis ogólny
Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The pathways that induce the effects of G-CSF are PI3K, ERK1/2 and p38. The generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow are the main functions of G-CSF. There are additional activities attributed to G-CSF such as neuroprotection, immunomodulation and generation of cardiac cells and dendritic cells. Large quantities of G-CSF are secreted in a variety of myeloid and non-myeloid cancers and rheumatoid arthritis
Monoclonal anti-granulocyte colony stimulating factor recognizes mouse G-CSF. The antibody shows less than 0.06% cross-reactivity with recombinant human G-CSF.
Monoclonal anti-granulocyte colony stimulating factor recognizes mouse G-CSF. The antibody shows less than 0.06% cross-reactivity with recombinant human G-CSF.
Immunogen
purified, recombinant mouse granulocyte colony stimulating factor, expressed in E. coli.
Zastosowanie
Anti-granulocyte colony stimulating factor antibody may be used for immunoblotting at a working concentration of 1-2 μg/ml. For ELISA the recommended concentration range is 2-8 μg/ml. The antibody is also suitable for neutralization assays.
Postać fizyczna
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
13 - Non Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
Certyfikaty analizy (CoA)
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