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F1395

Sigma-Aldrich

β-L-Fucose 1-phosphate bis(cyclohexylammonium) salt

≥98%

Synonim(y):

6-Deoxy-β-L-galactose 1-phosphate

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About This Item

Wzór empiryczny (zapis Hilla):
C6H11O8P · 2C6H14N
Masa cząsteczkowa:
442.48
Numer MDL:
MFCD22681514
Kod UNSPSC:
12352201
Identyfikator substancji w PubChem:
329799679
NACRES:
NA.25

Próba

≥98%

Postać

powder

metody

thin layer chromatography (TLC): suitable

rozpuszczalność

H2O: soluble 50 mg/mL, clear, colorless

temp. przechowywania

−20°C

ciąg SMILES

NC1CCCCC1.NC2CCCCC2.C[C@@H]3O[C@H](OP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]3O

InChI

1S/2C6H13N.C6H13O8P/c2*7-6-4-2-1-3-5-6;1-2-3(7)4(8)5(9)6(13-2)14-15(10,11)12/h2*6H,1-5,7H2;2-9H,1H3,(H2,10,11,12)/t;;2-,3+,4+,5-,6+/m..0/s1

Klucz InChI

FQMPFZHILABVMA-PEJHDPODSA-N

Zastosowanie

β-L-Fucose 1-phosphate is suitable as both substrate and product to identify, differentiate and characterize GTP fucose pyrophosphorylase(s) (GFPP; fucose-1-phosphate guanylyltransferases) involved in the formation of the nucleotide-sugar GDP-beta-l-fucose and other fucosylation donor substrates such as 3,3′-Diaminobenzidine (GDP)-β-l-fucose. β-L-Fucose 1-phosphate may be used to generate new fucosylation donor substrates for use in glycan fucosylation research.

Inne uwagi

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Certyfikaty analizy (CoA)

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Odwiedź Bibliotekę dokumentów

Toshihisa Kotake et al.
The Journal of biological chemistry, 283(13), 8125-8135 (2008-01-18)
Monomeric sugars generated during the metabolism of polysaccharides, glycoproteins, and glycolipids are imported to the cytoplasm and converted to respective nucleotide sugars via monosaccharide 1-phosphates, to be reutilized as activated sugars. Because L-fucose (L-Fuc) is activated mainly in the form
Leonie Engels et al.
Glycobiology, 24(2), 170-178 (2013-11-20)
Fucosyltransferases (FucTs) are essential tools for the synthesis of fucosylated glycoconjugates. Multistep enzyme catalysis of fucosylated glycans is not limited as long as isolated and well-characterized FucTs are available. The present paper introduces a novel bacterial α1,2-FucT of the glycosyltransferase
Bing Ma et al.
Glycobiology, 16(12), 158R-184R (2006-09-16)
Fucosylated carbohydrate structures are involved in a variety of biological and pathological processes in eukaryotic organisms including tissue development, angiogenesis, fertilization, cell adhesion, inflammation, and tumor metastasis. In contrast, fucosylation appears less common in prokaryotic organisms and has been suggested
GDP-L-fucose pyrophosphorylase. Purification, cDNA cloning, and properties of the enzyme.
Pastuszak I, Ketchum C, Hermanson G, et al.
The Journal of Biological Chemistry, 4273, 30165-30174 (1998)
Stephen Quirk et al.
Biochemistry, 44(39), 13172-13178 (2005-09-28)
GTP-l-fucose pyrophosphorylase(GFPP) catalyzes the reversible formation of the nucleotide-sugar GDP-beta-l-fucose from guanosine triphosphate and beta-l-fucose-1-phosphate. The enzyme functions primarily in the mammalian liver and kidney to salvage free fucose during the breakdown of glycoproteins and glycolipids. GFPP shares little primary
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