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Dokumenty

E4250

(−)-Epinephrine

Name: (−)-Epinephrine
Brand: SIGMA

Synonim(y):

(−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine

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About This Item

Wzór liniowy:

(HO)₂C₆H₃CH(OH)CH₂NHCH₃

Numer CAS:

51-43-4

Masa cząsteczkowa:

183.20

Beilstein:

2368277

Numer WE:

200-098-7

Numer MDL:

MFCD00002204

Kod UNSPSC:

12352200

Identyfikator substancji w PubChem:

24894545

NACRES:

NA.77

Poziom jakości

200

mp

215 °C (dec.) (lit.)

temp. przechowywania

2-8°C

ciąg SMILES

CNC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1

Klucz InChI

UCTWMZQNUQWSLP-VIFPVBQESA-N

informacje o genach

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)
rat ... Adra1a(29412) , Adra2a(25083) , Adrb1(24925) , Adrb2(24176) , Drd1a(24316) , Drd2(24318)

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Działania biochem./fizjol.

Adrenoceptor agonist.

Cechy i korzyści

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors and β-Adrenoceptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Rekonstytucja

This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50 mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.

This page may contain text that has been machine translated.

Piktogramy

GHS06

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H301 + H331 - H310

Zwroty wskazujące środki ostrożności

P261 - P262 - P280 - P301 + P310 - P302 + P352 + P310 - P304 + P340 + P311

Klasyfikacja zagrożeń

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Kod klasy składowania

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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Odwiedź Bibliotekę dokumentów

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Clonorchis sinensis is a group I bio-carcinogen responsible for cholangiocarcinoma (CHCA) in humans. However, the mechanism by which C. sinensis promotes carcinogenesis is unclear. Using the human cholangiocyte line H69, we investigated cell proliferation and gap junction protein expression after

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Journal of dairy science, 104(1), 1099-1110 (2020-11-10)

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Adipogenic and lipolytic effects of chronic glucocorticoid exposure.

Jonathan E Campbell et al.

American journal of physiology. Cell physiology, 300(1), C198-C209 (2010-10-15)

Glucocorticoids have been proposed to be both adipogenic and lipolytic in action within adipose tissue, although it is unknown whether these actions can occur simultaneously. Here we investigate both the in vitro and in vivo effects of corticosterone (Cort) on

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M A Velazquez et al.

Reproduction (Cambridge, England), 141(1), 91-103 (2010-10-12)

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Cryptococcus gattii virulence composite: candidate genes revealed by microarray analysis of high and less virulent Vancouver island outbreak strains.

Popchai Ngamskulrungroj et al.

PloS one, 6(1), e16076-e16076 (2011-01-21)

Human and animal cryptococcosis due to an unusual molecular type of Cryptococcus gattii (VGII) emerged recently on Vancouver Island, Canada. Unlike C. neoformans, C. gattii causes disease mainly in immunocompetent hosts, despite producing a similar suite of virulence determinants. To

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