B4750

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride

trypsin substrate

• Synonim(y): BANA, N_α-Benzoyl-DL-arginine-2-naphthylamide hydrochloride
• Wzór empiryczny (zapis Hilla): C₂₃H₂₅N₅O₂ · HCl
• Numer CAS: 913-04-2
• Masa cząsteczkowa: 439.94
• Beilstein: 3823291
• Numer WE: 213-015-4
• Numer MDL: MFCD00038940
• Kod UNSPSC: 12352204
• Identyfikator substancji w PubChem: 24891699
• NACRES: NA.32

Właściwości

• Próba: ≥98% (TLC)
• Postać: powder
• rozpuszczalność: DMF: 50 mg/mL, clear, colorless to faintly yellow
• temp. przechowywania: 2-8°C
• ciąg SMILES: Cl[H].NC(=N)NCCCC(NC(=O)c1ccccc1)C(=O)Nc2ccc3ccccc3c2
• InChI: 1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,29)(H4,24,25,26);1H
• Klucz InChI: BNGRKDJZQIGWQF-UHFFFAOYSA-N

Opis

Zastosowanie

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride has been used as a substrate in the BANA test to evaluate the inhibitory activity of stefin. It has also been used as a substrate for the determination of Ki values of inhibitors toward trypsin.

Działania biochem./fizjol.

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride (BANA) helps to determine the activities of cathepsin B and papain. BANA test is also useful in identifying the number of periodontal sites with periodontal pathogens. Presence of volatile sulfur compounds (VSCs), synthesized by oral bacteria in dental plaque or tongue coating can be colorimetrically confirmed by their ability to hydrolyze N-benzoyl-DL-arginine-2-naphthylamide.

Substraty

A chromogenic substrate for trypsin.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)