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A271
Anti-α2A Adrenergic Receptor antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonim(y):
Anti-ADRA2, Anti-ADRA2R, Anti-ADRAR, Anti-ALPHA2AAR, Anti-ZNF32
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About This Item
białko sprzężone:
unconjugated
application:
IHC (p)
WB
WB
klon:
polyclonal
reaktywność gatunkowa:
rat, human, mouse, pig
citations:
6
metody:
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1000
western blot: 1:500
western blot: 1:500
Polecane produkty
pochodzenie biologiczne
rabbit
Poziom jakości
białko sprzężone
unconjugated
forma przeciwciała
affinity isolated antibody
rodzaj przeciwciała
primary antibodies
klon
polyclonal
Formularz
buffered aqueous solution
masa cząsteczkowa
antigen ~45 kDa
reaktywność gatunkowa
rat, human, mouse, pig
metody
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1000
western blot: 1:500
numer dostępu UniProt
Warunki transportu
dry ice
temp. przechowywania
−20°C
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
human ... ADRA2A(150)
mouse ... Adra2a(11551)
rat ... Adra2a(25083)
Powiązane kategorie
Opis ogólny
Adrenergic receptors (ARs) belong to the 7-transmembrane domain G protein-coupled receptor superfamily that binds to the endogenous catecholamines, epinephrine and norepinephrine. α2AR subtypes block adenylyl cyclase, suppress voltage-sensitive Ca2+ channels, and stimulate receptor dependent K+ channels. All of the α2AR subtypes inhibit adenylyl cyclase through coupling to members of the Gi/Go class of G proteins. They are an important component of the neural circuitry and modulate cardiovascular physiology. The physiological function of the α2ARs in the kidney is to regulate Na+/H+ exchange.
Anti-α2A adrenergic receptor detects rat and mouse α2A adrenergic receptors by immunoblotting and immunohistochemistry. In immunoblotting, the antibody detects an approx. 45kDa band representing α2A receptors in tissues expressing this receptor subtype, although some non-specific bands have also been observed in certain cases.
Anti-α2A adrenergic receptor detects rat and mouse α2A adrenergic receptors by immunoblotting and immunohistochemistry. In immunoblotting, the antibody detects an approx. 45kDa band representing α2A receptors in tissues expressing this receptor subtype, although some non-specific bands have also been observed in certain cases.
Immunogen
synthetic peptide derived from amino acids 218-235 of human, mouse, rat, and pig α2A adrenergic receptor. The immunogen sequence is found within the third intracellular loop of the α2A adrenergic receptor subtype.
Zastosowanie
Rabbit anti-α2A adrenergic receptor antibody can be used for western blot (1:500) and immunohistochemistry (1:1000) applications.
Postać fizyczna
Solution in phosphate buffered saline, containing 1 mg/ml BSA and 0.05% sodium azide.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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