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Atto MB2 maleimide
Methylene Blue derivative, ≥90% (HPLC)
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About This Item
Kod UNSPSC:
12352111
NACRES:
NA.32
Polecane produkty
Poziom jakości
Próba
≥90% (HPLC)
≥90% (degree of coupling)
Postać
solid
producent / nazwa handlowa
ATTO-TEC GmbH
λ
in ethanol (with 0.1% trifluoroacetic acid)
absorpcja UV
λ: 655-661 nm Amax
temp. przechowywania
−20°C
Zastosowanie
ATTO MB2 is a derivative of the well-known redox dye Methylene Blue. The dye can be reversibly reduced to the colorless leuko form. Upon oxidation the dye recovers and the absorption is fully restored. In common with most ATTO-labels the dye shows a high extinction coefficient. The dye is moderately hydrophilic. ATTO MB2 is a cationic dye. After coupling to a substrate the dye carries a net electrical charge of +1. Maleimides are well suited for coupling to thiol groups. This is similar to iodacetamides, but maleimides react more selectively with thiols. They do not show significant reaction with histidine or methionine. Hydrolysis of maleimides to a mixture of isomeric nonreactive maleamic acids can compete significantly with thiol modification, particularly above pH 8. Maleimides may be used for labeling of amines, which usually requires a higher pH than reaction of maleimides with thiols.
Informacje prawne
This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.
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Kod klasy składowania
11 - Combustible Solids
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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