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Dokumenty

363M-1

Sigma-Aldrich

PAX-8 (MRQ-50) Mouse Monoclonal Antibody

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Wszystkie zdjęcia(1)

About This Item

Kod UNSPSC:
12352203
NACRES:
NA.41

pochodzenie biologiczne

mouse

Poziom jakości

100
500

białko sprzężone

unconjugated

forma przeciwciała

culture supernatant

rodzaj przeciwciała

primary antibodies

klon

MRQ-50, monoclonal

opis

For In Vitro Diagnostic Use in Select Regions (See Chart)

Postać

buffered aqueous solution

reaktywność gatunkowa

human

opakowanie

vial of 0.1 mL concentrate (363M-14)
vial of 0.5 mL concentrate (363M-15)
bottle of 1.0 mL predilute (363M-17)
vial of 1.0 mL concentrate (363M-16)
bottle of 7.0 mL predilute (363M-18)

producent / nazwa handlowa

Cell Marque™

metody

immunohistochemistry: 1:50-1:200

izotyp

IgG

Warunki transportu

wet ice

temp. przechowywania

2-8°C

informacje o genach

human ... PAX8(7849)

Opis ogólny

PAX-8 is a transcription factor expressed during embryonic development of Müllerian organs, kidneys, and thyroid, with continued expression in some epithelial cell types of these mature tissues.PAX-8 is a useful marker for neoplasms of gynecologic renal and thyroidorigin.PAX-8 (MRQ-50) antibody targets the N-terminus of the PAX-8 molecule. This section of the protein is shared with other PAX proteins such as PAX-5 and PAX-6; thus, some cross-reactivity with these proteins may be observed as evidenced by the labeling of selected lymphocytes, and neuroendocrine cells.

Jakość


IVD
IVD
IVD
RUO

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Uwaga dotycząca przygotowania

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Mark J Mentrikoski et al.
Applied immunohistochemistry & molecular morphology : AIMM, 22(9), 635-641 (2014-10-04)
Clear-cell renal cell carcinoma (CC-RCC) is the most common primary kidney malignancy, yet this morphology is not unique to renal primary tumors, as clear-cell variants of numerous nonrenal carcinomas of varying lineages exist. Therefore, because of CC-RCC's ability to metastasize
Inigo Espinosa et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 34(3), 257-265 (2015-04-07)
Breast carcinomas rarely metastasize to the ovary and are even more rarely present clinically as primary ovarian tumors. However, patients with breast cancer not infrequently develop independent primary ovarian carcinomas. In these cases, distinction between independent primaries and metastatic tumors
Biljana Pauzar et al.
Collegium antropologicum, 36 Suppl 2, 79-82 (2013-02-13)
US-guided fine needle aspiration cytology is currently the best diagnostic tool for thyroid nodules. However, it is not sensitive and specific enough for differentiating between benign and malignant follicular tumors. A potentially useful marker for this differentiation is the PAX8-PPARgamma
Control of sheath back bleeding: a simplified approach.
G I Gabliani et al.
Catheterization and cardiovascular diagnosis, 13(6), 427-427 (1987-11-01)
Meaghan L Barr et al.
Journal of clinical pathology, 68(1), 12-17 (2014-10-16)
Immunohistochemical stains have greatly improved the diagnostic accuracy of renal cell carcinoma (RCC) for primary and distant tumours. We evaluate a marker that has recently been incorporated in clinical practice, PAX-8, in primary and metastatic RCCs. Two distinct tissue microarrays
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