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156R-9

CD56 (MRQ-42) Rabbit Monoclonal Antibody

Name: CD56 (MRQ-42) Rabbit Monoclonal Antibody
Brand: SIGMA

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About This Item

Kod UNSPSC:

12352203

NACRES:

NA.41

Polecane produkty

Slide 1 of 2

1 of 2

Sigma-Aldrich

395R-1

c-Myc (EP121) Rabbit Monoclonal Primary Antibody

Sigma-Aldrich

ABS82

Anti-VEGF Antibody

pochodzenie biologiczne

rabbit

Poziom jakości

100
500

białko sprzężone

unconjugated

forma przeciwciała

culture supernatant

rodzaj przeciwciała

primary antibodies

klon

MRQ-42, monoclonal

opis

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formularz

buffered aqueous solution

reaktywność gatunkowa

human

opakowanie

vial of 0.1 mL concentrate (156R-94)
vial of 0.5 mL concentrate (156R-95)
bottle of 1.0 mL predilute (156R-97)
vial of 1.0 mL concentrate (156R-96)
bottle of 7.0 mL predilute (156R-98)

producent / nazwa handlowa

Cell Marque^™

metody

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

izotyp

IgG1

kontrola

neuroblastoma

Warunki transportu

wet ice

temp. przechowywania

2-8°C

wizualizacja

membranous

informacje o genach

human ... NCAM1(4684)

Opis ogólny

CD56, also known as a neural cell adhesion molecule (NCAM), is a calcium-independenthomophilic binding protein that belongs to a group of cell adhesion molecules includingcadherins, selectins, and integrins. CD56 is involved in cell-cell adhesion of neural cellsduring embryogenesis and is expressed in most neuroectodermally derived tissues. Innormal tissue, anti-CD56 labels neurons, glia, Schwann cells, NK (natural killer) cells, and asubset of T-cells. CD56 expression can be seen in most NK cell neoplasms,4 and is frequentlyused to identify neoplasms with neuroendocrine differentiation.

Jakość

IVD

RUO

Powiązanie

CD56 Positive Control Slides, Product No. 156S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Uwaga dotycząca przygotowania

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Hot spots of antigenicity in the neural cell adhesion molecule NCAM.

R Gerardy-Schahn et al.

International journal of cancer. Supplement = Journal international du cancer. Supplement, 8, 38-42 (1994-01-01)

Monoclonal antibodies (MAbs) ranked together as small-cell-lung-cancer (SCLC) Cluster I MAbs are directed against the neural cell adhesion molecule NCAM (CD 56) and have been shown to be useful reagents in SCLC diagnosis and therapy. We analyzed the epitopes recognized

Expression of neural cell adhesion molecule-related sialoglycoprotein in small cell lung cancer and neuroblastoma cell lines H69 and CHP-212.

C E Moolenaar et al.

Cancer research, 50(4), 1102-1106 (1990-02-15)

Monoclonal antibodies (MAbs) 123C3 and 123A8 generated against a membrane preparation of a small cell lung carcinoma (SCLC) specimen recognize not only SCLC and bronchial carcinoids but also a significant portion of non-small cell lung carcinomas (non-SCLC) of various histological

Neural cell adhesion molecule expression, neuroendocrine differentiation and prognosis in lung carcinoma.

R E Kibbelaar et al.

European journal of cancer (Oxford, England : 1990), 27(4), 431-435 (1991-01-01)

We investigated the expression of the neural cell adhesion molecule (NCAM) in a series of surgically resected lung carcinomas of various histological subtypes by means of a panel of monoclonal antibodies recognising different N-CAM epitopes. In a subgroup of 56

Expression of CD56/neural cell adhesion molecule correlates with the presence of lytic bone lesions in multiple myeloma and distinguishes myeloma from monoclonal gammopathy of undetermined significance and lymphomas with plasmacytoid differentiation.

Scott A Ely et al.

The American journal of pathology, 160(4), 1293-1299 (2002-04-12)

Unlike monoclonal gammopathy of undetermined significance (MGUS) or non-Hodgkin's lymphomas (NHLs) with plasmacytoid differentiation, multiple myeloma (MM) is commonly associated with lytic bone lesions. Although the mechanisms of increased osteoclast activity are partially understood, comparatively little is known about the

Natural killer cell lymphoma in the duodenum.

Masahiko Sumi et al.

Leukemia & lymphoma, 44(1), 201-204 (2003-04-15)

We present a case of duodenal non-Hodgkin lymphoma in a 71-year-old woman. Immunohistochemistry characterized the lymphoma cells as CD2(+); surface CD3(-) but cytoplasmic CD3(+); CD7(+); and CD56(+) without a rearrangement of the T-cell receptor gene. Cells had a high N/C

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